Mitosis of radial glial cells in the optic tectum of adult goldfish

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Mitosis of radial glial cells in the optic tectum of adult goldfish.

A class of tectal cells whose mitotic activity is enhanced by optic nerve regeneration in adult goldfish has been identified as radial neuroglia. These mitotic glial cells are morphologically distinct cells with prominent radial processes which extend through the entire depth of the tectal layers. The radial glia incorporate exogenous [3H]thymidine ([3H]TdR) into DNA as early as 2 hr after syst...

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Post-Proliferative Immature Radial Glial Cells Female-Specifically Express Aromatase in the Medaka Optic Tectum

Aromatase, the key enzyme responsible for estrogen biosynthesis, is present in the brain of all vertebrates. Much evidence has accumulated that aromatase is highly and exclusively expressed in proliferating mature radial glial cells in the brain of teleost fish even in adulthood, unlike in other vertebrates. However, the physiological significance of this expression remains unknown. We recently...

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Retinal terminals in the goldfish optic tectum: identification and characterization.

Retinal terminal profiles in the goldfish optic tectum were identified electron microscopically after (1) labeling with horseradish peroxidase and (2) in the early stages of degeneration in short-term eye enucleates. All labeled terminals shared certain common morphological characteristics which were identical to those of a population of terminals in normal tecta. Terminals of this type disappe...

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Lineage of radial glia in the chicken optic tectum.

In many parts of the central nervous system, the elongated processes of radial glial cells are believed to guide immature neurons from the ventricular zone to their sites of differentiation. To study the clonal relationships of radial glia to other neural cell types, we used a recombinant retrovirus to label precursor cells in the chick optic tectum with a heritable marker, the E. coli lacZ gen...

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Interactions between optic fibres controlling the locations of their terminals in the goldfish optic tectum.

Removal of the caudal half of a goldfish optic tectum induces optic fibres from the entire contralateral retina to terminate retinotopically within the remaining half. This compression has been viewed by some as the result of competition between the fibres and by others as a consequence of changes, induced by the surgery, in tectal labels guiding fibres to terminal sites. To distinguish between...

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ژورنال

عنوان ژورنال: The Journal of Neuroscience

سال: 1981

ISSN: 0270-6474,1529-2401

DOI: 10.1523/jneurosci.01-08-00862.1981